Technologies
 







Barry J.J.A., Silva M.M.C.G., Popov V.K., Shakesheff K.M., Howdle S.M. Supercritical carbon dioxide: putting the fizz into biomaterials. Philosophical Transactions: Mathematical, Physical and Engineering Sciences 2006 364 (1838): 249 – 261.

Thomas R.J., Bennett A., Thomson B., Shakesheff K.M. Hepatic stellate cells on poly(DL-lactic acid) surfaces control the formation of 3D hepatocyte co-culture aggregates in vitro. Eur Cell Mater. 2006 11:16-26.

Cyster L.A., Grant D.M., Howdle S.M., Rose F.R., Irvine D.J., Freeman D., Scotchford C.A., Shakesheff K.M. The influence of dispersant concentration on the pore morphology of hydroxyapatite ceramics for bone tissue engineering. Biomaterials 2005; 26(7): 697-702.

Whitaker, M.J., Hao, J.Y., Davies, O.R., Serhatkulu, G., Stolnik-Trenkic, S., Howdle, S.M., Shakesheff, K.M. The production of protein-loaded microparticles by supercritical fluid enhanced mixing and spraying. J. Control. Release 2005; 101 (1-3): 85-92 Sp. Iss. SI.

Hou Q.P., De Bank P.A., Shakesheff K.M. Injectable scaffolds for tissue regeneration J. Mater. Chem. 2004; 14 (13): 1915-1923

Woods H.M., Silva M.M.C.G., Nouvel C., Shakesheff K.M., Howdle S.M. Materials processing in supercritical carbon dioxide: surfactants, polymers and biomaterials J. Mater. Chem. 2004; 14 (11): 1663-1678

Hao J.Y., Whitaker M.J., Wong B., Serhatkulu G., Shakesheff K.M., Howdle S.M Plasticization and spraying of poly (DL-lactic acid) using supercritical carbon dioxide: Control of particle size J. Pharm. Sci. 2004; 93 (4): 1083-1090

Rose F.R., Hou Q., Oreffo R.O. Delivery systems for bone growth factors - the new players in skeletal regeneration J. Pharm. Pharmacol. 2004; 56(4): 415-27

Quirk, R.A., France, R.M., Shakesheff, K.M., Howdle, S.M. Supercritical fluid technologies and tissue engineering scaffolds. Curr. Opin. Solid St. M. 2004; 8 (3-4): 313-32.

Salem, A. K., Rose, F. R. A. J., Oreffo, R. O. C., Yang, X. B., Davies, M. C., Mitchell, J. R., Roberts, C. J., Stolnik-Trenkic, S., Tendler, S. J. B., Williams, P. M., and Shakesheff, K. M. Porous polymer and cell composites that self-assemble in situ. Adv. Mater. 2003, 15, 205-210.

Pearson, R. G., Molino, Y., Williams, P. M., Tendler, S. J., Davies, M. C., Roberts, C. J., and Shakesheff, K. M. Spatial confinement of neurite regrowth from dorsal root ganglia within nonporous microconduits. Tissue Eng. 2003, 9, 201-208.

Riccalton-Banks, L., Liew, C., Bhandari, R., Fry, J., and Shakesheff, K. Long-term culture of functional liver tissue: three-dimensional coculture of primary hepatocytes and stellate cells. Tissue Eng. 2003, 9, 401-410.

De Bank, P. A., Kellam, B., Kendall, D. A., and Shakesheff, K. M. Surface engineering of living myoblasts via selective periodate oxidation. Biotechnol. Bioeng. 2003, 81, 800-808.

Kellam B., De Bank P.A., Shakesheff K.M. Chemical modification of mammalian cell surfaces Chem. Soc. Rev. 2003; 32 (6): 327-337

Watson, M. S., Whitaker, M. J., Howdle, S. M., and Shakesheff, K. M. Incorporation of proteins into polymer materials by a novel supercritical fluid processing method. Adv. Mater. 2002, 14, 1802-1804.

Howard, D., Partridge, K., Yang, X., Clarke, N. M., Okubo, Y., Bessho, K., Howdle, S. M., Shakesheff, K. M., and Oreffo, R. O. Immunoselection and adenoviral genetic modulation of human osteoprogenitors: in vivo bone formation on PLA scaffold. Biochem. Biophys. Res. Commun. 2002, 299, 208-215.

Quirk, R. A., Davies, M. C., Tendler, S. J. B., Chan, W. C., and Shakesheff, K. M. Controlling biological interactions with poly(lactic acid) by surface entrapment modification. Langmuir 2001, 17, 2817-2820.

Quirk, R. A., Chan, W. C., Davies, M. C., Tendler, S. J., and Shakesheff, K. M. Poly(L-lysine)-GRGDS as a biomimetic surface modifier for poly(lactic acid). Biomaterials 2001, 22, 865-872.

Howdle, S. M., Watson, M. S., Whitaker, M. J., Popov, V. K., Davies, M. C., Mandel, F. S., Wang, J. D., and Shakesheff, K. M. Supercritical fluid mixing: preparation of thermally sensitive polymer composites containing bioactive materials. Chem. Commun. 2001, 109-110.

Whitaker, M. J., Quirk, R. A., Howdle, S. M., and Shakesheff, K. M. Growth factor release from tissue engineering scaffolds. J. Pharm. Pharmacol. 2001, 53, 1427-1437.

Yang, X. B., Roach, H. I., Clarke, N. M., Howdle, S. M., Quirk, R., Shakesheff, K. M., and Oreffo, R. O. Human osteoprogenitor growth and differentiation on synthetic biodegradable structures after surface modification. Bone 2001, 29, 523-531.